Hematopoietic cell transplantation and emerging viral infections
Identifieur interne : 002807 ( Main/Exploration ); précédent : 002806; suivant : 002808Hematopoietic cell transplantation and emerging viral infections
Auteurs : D. Chatzidimitriou [Grèce] ; E. Gavriilaki [Grèce] ; I. Sakellari [Grèce] ; E. Diza [Grèce]Source :
- Journal of Medical Virology [ 0146-6615 ] ; 2010-03.
English descriptors
- Teeft :
- Acute leukemia, Allander, Allogeneic, Allogeneic bone marrow transplantation, Allogeneic hematopoietic cell transplantation, Allogeneic transplant, Allogeneic transplantation, Antiviral, Asymptomatic, Autologous, Bocavirus, Boeckh, Bone marrow transplant, Bronchoalveolar, Bronchoalveolar lavage, Bronchoalveolar lavage samples, Cell transplant, Cell transplant recipients, Cell transplantation, Cell transplants, Chan, Cidofovir, Clin, Clin microbiol, Clinical symptoms, Combination therapy, Coronavirus, Coronaviruses, Cystitis, Donor, Emerg, Epidemiology, Ganciclovir, Genetic variability, Graft, Gvhd, Hbov, Hbov infection, Hematopoietic, Hematopoietic cell transplant recipients, Hematopoietic cell transplantation, Hematopoietic graft recipients, Hematopoietic transplant, Hematopoietic transplant recipients, Hemorrhagic, Hemorrhagic cystitis, Herpesvirus, Hmpv, Hmpv infection, Hoek, Human bocavirus, Human coronavirus, Human coronaviruses, Human herpesvirus, Human metapneumovirus, Human metapneumovirus infection, Immunocompromised, Immunocompromised patients, Infection, Infectious complications, Kahn, Kawasaki disease, Laboratory diagnosis, Lavage, Leukoencephalopathy, Limited data, Ljungman, Marrow, Metapneumovirus, Metapneumovirus infection, Microbiol, Multifocal, Nasopharyngeal aspirates, Pathogen, Pediatr, Pediatric, Pityriasis rosea, Pneumonia, Polyomaviruses, Primary infection, Primer, Proc natl acad, Progressive multifocal leukoencephalopathy, Reactivation, Recent study, Recipient, Respiratory disease, Respiratory tract, Respiratory tract disease, Respiratory tract infections, Respiratory viruses, Risk factors, Schildgen, Tract infections, Transplant, Transplantation, Unrelated donors, Viral, Viral infections, Virol, Young children.
Abstract
Viral infections remain important causes of morbidity and mortality in hematopoietic cell transplant recipients. More recent developments in preparative regimens and graft manipulations, as well as the control of well‐recognized post‐transplant infections by the introduction of prophylaxis and preemptive strategies, have influenced the timing and the epidemiology of infections. As new pathogens, such as human metapneumovirus (HMPV), human bocavirus, human coronaviruses HCoV‐NL63 and HCoV‐HKU1, human herpesviruses HHV‐6 and HHV‐7, and polyomaviruses, have emerged, it is fundamental to determine the significance of the newly discovered viruses and their role in the transplantation field. This article summarizes recent data on epidemiology and laboratory diagnosis of new pathogens, as well as clinical features and management of the associated infectious complications. J. Med. Virol. 82:528–538, 2010. © 2010 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/jmv.21696
Affiliations:
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Diza</name><affiliation wicri:level="1"><country xml:lang="fr">Grèce</country><wicri:regionArea>2nd Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="ISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><imprint><biblScope unit="vol">82</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="528">528</biblScope><biblScope unit="page" to="538">538</biblScope><biblScope unit="page-count">11</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-03">2010-03</date></imprint><idno type="ISSN">0146-6615</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0146-6615</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acute leukemia</term><term>Allander</term><term>Allogeneic</term><term>Allogeneic bone marrow transplantation</term><term>Allogeneic hematopoietic cell transplantation</term><term>Allogeneic transplant</term><term>Allogeneic transplantation</term><term>Antiviral</term><term>Asymptomatic</term><term>Autologous</term><term>Bocavirus</term><term>Boeckh</term><term>Bone marrow transplant</term><term>Bronchoalveolar</term><term>Bronchoalveolar lavage</term><term>Bronchoalveolar lavage samples</term><term>Cell transplant</term><term>Cell transplant recipients</term><term>Cell transplantation</term><term>Cell transplants</term><term>Chan</term><term>Cidofovir</term><term>Clin</term><term>Clin microbiol</term><term>Clinical symptoms</term><term>Combination therapy</term><term>Coronavirus</term><term>Coronaviruses</term><term>Cystitis</term><term>Donor</term><term>Emerg</term><term>Epidemiology</term><term>Ganciclovir</term><term>Genetic variability</term><term>Graft</term><term>Gvhd</term><term>Hbov</term><term>Hbov infection</term><term>Hematopoietic</term><term>Hematopoietic cell transplant recipients</term><term>Hematopoietic cell transplantation</term><term>Hematopoietic graft recipients</term><term>Hematopoietic transplant</term><term>Hematopoietic transplant recipients</term><term>Hemorrhagic</term><term>Hemorrhagic cystitis</term><term>Herpesvirus</term><term>Hmpv</term><term>Hmpv infection</term><term>Hoek</term><term>Human bocavirus</term><term>Human coronavirus</term><term>Human coronaviruses</term><term>Human herpesvirus</term><term>Human metapneumovirus</term><term>Human metapneumovirus infection</term><term>Immunocompromised</term><term>Immunocompromised patients</term><term>Infection</term><term>Infectious complications</term><term>Kahn</term><term>Kawasaki disease</term><term>Laboratory diagnosis</term><term>Lavage</term><term>Leukoencephalopathy</term><term>Limited data</term><term>Ljungman</term><term>Marrow</term><term>Metapneumovirus</term><term>Metapneumovirus infection</term><term>Microbiol</term><term>Multifocal</term><term>Nasopharyngeal aspirates</term><term>Pathogen</term><term>Pediatr</term><term>Pediatric</term><term>Pityriasis rosea</term><term>Pneumonia</term><term>Polyomaviruses</term><term>Primary infection</term><term>Primer</term><term>Proc natl acad</term><term>Progressive multifocal leukoencephalopathy</term><term>Reactivation</term><term>Recent study</term><term>Recipient</term><term>Respiratory disease</term><term>Respiratory tract</term><term>Respiratory tract disease</term><term>Respiratory tract infections</term><term>Respiratory viruses</term><term>Risk factors</term><term>Schildgen</term><term>Tract infections</term><term>Transplant</term><term>Transplantation</term><term>Unrelated donors</term><term>Viral</term><term>Viral infections</term><term>Virol</term><term>Young children</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Viral infections remain important causes of morbidity and mortality in hematopoietic cell transplant recipients. More recent developments in preparative regimens and graft manipulations, as well as the control of well‐recognized post‐transplant infections by the introduction of prophylaxis and preemptive strategies, have influenced the timing and the epidemiology of infections. As new pathogens, such as human metapneumovirus (HMPV), human bocavirus, human coronaviruses HCoV‐NL63 and HCoV‐HKU1, human herpesviruses HHV‐6 and HHV‐7, and polyomaviruses, have emerged, it is fundamental to determine the significance of the newly discovered viruses and their role in the transplantation field. This article summarizes recent data on epidemiology and laboratory diagnosis of new pathogens, as well as clinical features and management of the associated infectious complications. J. Med. Virol. 82:528–538, 2010. © 2010 Wiley‐Liss, Inc.</div></front></TEI><affiliations><list><country><li>Grèce</li></country></list><tree><country name="Grèce"><noRegion><name sortKey="Chatzidimitriou, D" sort="Chatzidimitriou, D" uniqKey="Chatzidimitriou D" first="D." last="Chatzidimitriou">D. Chatzidimitriou</name></noRegion><name sortKey="Chatzidimitriou, D" sort="Chatzidimitriou, D" uniqKey="Chatzidimitriou D" first="D." last="Chatzidimitriou">D. Chatzidimitriou</name><name sortKey="Chatzidimitriou, D" sort="Chatzidimitriou, D" uniqKey="Chatzidimitriou D" first="D." last="Chatzidimitriou">D. Chatzidimitriou</name><name sortKey="Diza, E" sort="Diza, E" uniqKey="Diza E" first="E." last="Diza">E. Diza</name><name sortKey="Gavriilaki, E" sort="Gavriilaki, E" uniqKey="Gavriilaki E" first="E." last="Gavriilaki">E. Gavriilaki</name><name sortKey="Sakellari, I" sort="Sakellari, I" uniqKey="Sakellari I" first="I." last="Sakellari">I. 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